Gene defect responsible for chronic intestine inflammations?
Disease Crohn in the lower small intestine (openPR) - an Canadian-American researcher team assumed that a certain gene variant favours the emergence of a chronically inflammatory intestine illness, reports today the diploma Ernährungswissenschaftlerin Judith Männich of the society for nourishing medicine and Diät
etik registered association made of Aachen.Chronically inflammatory intestine illnesses such as disease Crohn and Colitis ulcerosa arise both within families and in certain ethnical groups frequently up, what suggests a genetic connection. Current study results of an Canadian-American researcher team encourage these assumptions. The investigations showed clear connections of a certain gene variant and the occurrence of a chronically inflammatory intestine illness. It concerns thereby Interleukin, a messenger material of the immune system, which on the one hand bacteria fought and on the other hand is involved into inflammation processes (1).
In the context of the study the researcher team examined the hereditary property of 547 patients with disease Crohn around Richard dry and compared this afterwards with the hereditary property of 548 healthy persons. Here clearly genetic differences showed up, whereby the healthy control persons possessed a crucial gene variant four times more frequently than the gotten sick ones.
To further investigations at animals it pointed itself that the absence of this gene variant entails a decreased answer to inflammation attractions in the intestine. The researchers expect from it new starting points in the medicament research, which possibly prevent the inflammatory process.
A test row with an anti-body showed already first successes. Via the key role of the Interleukins in immune system could further starting points for the treatment and therapy of other autoimmune illnesses take place. By an individually adapted nourishing therapy, for example a light full food, clear improvements of the general state of patients can be obtained, stress the Ernährungswissenschaftlerin finally. Further information receives you under www.ernaehrungsmed.de. 2,496 indications
Literature:
(1) Richard dry et al. : A Genome Wide Association Study Identifies IL23R
as at Inflammatory Bowel Disease of genes Science 1 December 2006: Volume.
314. No. 5804, pp. 1403 - 1405 DOI: 10.1126/science.1136668
The society for nourishing medicine and Diätetik registered association.
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The society for nourishing medicine and Diätetik registered association.
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